DEPARTMENTS/
LABORATORIES
LABORATORIES
Protein Degradation
Faculty
Introduction
‘Understanding and harnessing the protein degradation code’
‘Understanding and harnessing the protein degradation code’
The ubiquitin-proteasome system regulates numerous biological pathways through selective degradation of unwanted proteins. Its defects lead to various diseases such as cancer, inflammation, and neurodegeneration. We aim to elucidate the mechanisms by which proteins are timely and efficiently ubiquitylated and degraded to achieve cellular health.